Bsp bone
WebBone sialoprotein (BSP) is an acidic, phosphorylated glycoprotein that is synthesized by osteoblasts and osteoclastic-like cells in culture. It has an unglycosylated mass of 33 kDa (glycosylated, 70–80 kDa). Although the function of BSP is still not fully understood, BSP stimulates hydroxyapatite formation in vitro and appears to mediate cell ... WebBone sialoprotein (BSP) is an acidic, phosphorylated glycoprotein that is synthesized by osteoblasts and osteoclastic-like cells in culture. It has an unglycosylated mass of 33 kDa (glycosylated, 70–80 kDa). Although the function of BSP is still not fully understood, BSP stimulates hydroxyapatite formation in vitro and appears to mediate cell ...
Bsp bone
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WebOct 14, 2024 · Similarly, He et al. revealed that the serum levels of BSP could be used to evaluate bone metastasis, with a cut-off value of 33.56 ng/ml, sensitivity of 77.8, and specificity of 81.1%. Collectively, these findings indicated that BSP is a stable component of a bone metastasis predictive model, like in the study conducted by Zhou et al. . WebMar 21, 2014 · Background Osteogenesis is a highly regulated developmental process and continues during the turnover and repair of mature bone. Runx2, the master regulator of osteoblastogenesis, directs a transcriptional program essential for bone formation through genetic and epigenetic mechanisms. While individual Runx2 gene targets have been …
WebBSP is a marker of bone metabolism, which can activate osteoblasts, dental osteocyte, or osteoblast like cells, and promote the differentiation of cells into osteoblasts, thus leading to bone mineralization. 31,32 Due to the high expression of BSP in differentiated and mature osteoblasts, BSP can be used as a late marker of osteogenic ...
WebBone sialoprotein (BSP) is an acidic, noncollagenous glycoprotein abundantly expressed in mineralized tissues. Although BSP is frequently used as a marker of osteoblast … WebFeb 5, 2024 · Bone homeostasis is proverbial for being essentially directed by Wnt-mediated signals . By binding to low-density lipoprotein receptor-related protein 5/6 (LRP5/6), this cascade can be blocked by antagonists such as Dickkopf-1 (DKK-1) [ 52 ]. β-catenin/Wnt pathway can inhibit DPSCs differentiation [ 53 ].
WebBone Sialoprotein Structure of Growth Plate and Bone Matrix. Bone sialoprotein is the second major sialoprotein of bone [2 ]. It is also... Biochemical Dynamics. MARKUS J. …
Bone sialoprotein (BSP) is a component of mineralized tissues such as bone, dentin, cementum and calcified cartilage. BSP is a significant component of the bone extracellular matrix and has been suggested to constitute approximately 8% of all non-collagenous proteins found in bone and cementum. BSP, a … See more Native BSP has an apparent molecular weight of 60-80 kDa based on SDS-PAGE, which is a considerable deviation from the predicted weight (based on cDNA sequence) of approximately 33 kDa. The mammalian BSP … See more The amount of BSP in bone and dentin is roughly equal, however the function of BSP in these mineralized tissues is not known. One possibility is that BSP acts as a nucleus for the formation of the first apatite crystals. As the apatite forms along the collagen fibres … See more • Human IBSP genome location and IBSP gene details page in the UCSC Genome Browser. See more • Karadag A, Fisher LW (2006). "Bone sialoprotein enhances migration of bone marrow stromal cells through matrices by bridging MMP-2 to alpha(v)beta3-integrin". J. Bone Miner. Res. … See more product from taiwanWebFeb 24, 2024 · BSP stands for Binary Space Partitioning and is a technique used to store data for a 3D World. Quake was one of the first games to use this technique, and many … product from the high plains of boliviaWebOsteoporosis is a systemic metabolic bone disease characterized by a reduction in bone mass, bone quality, and microarchitectural deterioration. ... was confirmed that the bone formation effect induced by the above natural products was regulated by the expressions of bone specific matrix proteins (ALP, BSP, OCN, OPN, COL I), transcription ... rekinect amanda harrisWebPrior studies have demonstrated that the pineal hormone, melatonin, can stimulate chloramphenicol acetyltransferase activity in Drosophila SL-3 cells transfected with a chloramphenicol acetyltransferase reporter construct containing the response element of rat bone sialoprotein (BSP). Based on these findings, studies were performed to determine … product from 意味WebApr 28, 2000 · Bone sialoprotein (BSP) is a secreted glycoprotein primarily found in sites of biomineralization. Recently, we demonstrated that BSP is strongly upregulated in osteotropic cancers and particularly those that exhibit microcalcifications. BSP contains an Arg-Gly-Asp (RGD) motif found in other adhesive molecules that interact with cellular … product from japanWeb2. Bone sialoprotein. Human bone sialoprotein (BSP), a 33 kDa glycoprotein, is a major non-collagenous extracellular protein of mineralized tissues such as bone, dentin, cementum, and calcified cartilage [].BSP has an apparent molecular weight of 60–80 kDa due to extensive post-translational modifications including N-and O-linked glycosylation, … product frontWebBSP: [ brōm-sul´fah-lēn ] trademark for a preparation of sulfobromophthalein sodium, a dye used in a liver function test called the sulfobromophthalein test . product frozen during shipping liability