Cromogranine
WebAug 2, 2024 · Chromogranin A (CgA) is an acidic secretory glycoprotein found in the secretory granules of neuroendocrine cells and neurons, as is a member of the granin family of proteins. It can be used both for immunohistochemical stains and as a serum marker 4.. Immunohistochemistry. Chromogranin A is useful in identifying tissues of … WebChromogranin A (CGA) is a 439-amino acid protein with a molecular weight of 48 to 60 kDa, depending on glycosylation and phosphorylation status. It is a member of the granin …
Cromogranine
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Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins. As such, it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in the pancreas. In humans, chromogranin A protein is encoded by the CHGA gene. WebChromogranin A is physiologically degraded by tissue-specific proteases such as plasmin. Levels and activities of tissue plasminogen activator are reduced in inflammatory, diabetic vascular tissues and in smoking; therefore, this reduction may contribute to impaired CgA turnover. Vasostatin-1, produced by proteolytic cleavage of CgA, inhibits ...
WebApr 11, 2024 · Chromogranin definition: a protein released by neuroendocrine cells Meaning, pronunciation, translations and examples WebChromogranin A is a protein released from neuroendocrine cells. These are cells that secrete hormones in response to signals from the nervous system. They are found in …
WebGet better batch-to-batch reproducibility with a recombinant antibody Anti-Chromogranin A antibody [EPR22537-249] (ab254557) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by recombinant technology for fast production WebProduct ID:chromogranin-a. Antigen Background. Chromogranin A is a 68 kD acidic protein which is reported to be widely expressed in neural tissues and in secretory …
WebApr 27, 2024 · Clinical use Serum Chromogranin A measurements are a first-line test for diagnosing carcinoid tumours, in conjunction with, or as an alternative to urine 5-hydroxyindoleacetic acid (5-HIAA). Background Because of its ubiquitous distribution within neuroendocrine tissues, chromogranin A is a useful diagnostic marker for …
WebChromogranin A 1 is a hydrophilic glycoprotein that is stored in the chromaffin granules of the neuroendocrine cells. 2 The physiologic role of CgA has not been fully elucidated, but studies suggest that it serves as a precursor to other biologically active peptides and facilitates the production of other hormones and neuropeptides. 2-4 In healthy … evaluating gans in medical imagingWebAbstract. Circulating neuron-specific enolase (NSE) and chromogranin A (CgA) were measured in 128 patients with neuroendocrine tumours (NET) to compare their sensitivity and specificity, to investigate factors associated with elevated serum levels and to determine the usefulness of these markers in the follow-up of NET patients. evaluating generated text as text generationWebSep 24, 2024 · Chromogranin A is a secretory protein, composed of 439 amino acids, found in the large dense-core vesicles of the neuroendocrine cells. It belongs to the … evaluating gender bias in psychologyWebChromogranin A is a 68 kD acidic protein which is reported to be widely expressed in neural tissues and in secretory granules of human endocrine cells, for example, parathyroid gland, adrenal medulla, anterior pituitary gland, islet cells of the pancreas and C cells of the thyroid. Chromogranin A expression has been reported in neuroendocrine ... first black nfl player 1933WebOct 17, 2015 · Chromogranin A (CgA) A blood tumor marker used for detection of certain cancers. Chromogranin A is considered the best general neuroendocrine serum or … first black nfl football playerWeb保存条件： SYP/Synaptophysin Rabbit Polyclonal Antibody -20ºC保存，Western一抗稀释液-20ºC或4ºC保存，一年有效。Western一抗稀释液优先推荐4ºC保存，长期不使用可以考虑-20ºC保存，但冻融可能会导致出现轻微的浑浊和少量不溶物。 first black nfl hall of fameWebChromogranins. The chromogranins (types A, B, and C) are a group of monomeric proteins that compose the major portion of the soluble protein extract of the … first black nurse in canada